HitPredict

Interactor 1: RHG32 (A7KAX9)
Rho GTPase-activating protein 32 (Brain-specific Rho GTPase-activating protein) (GAB-associated Cdc42/Rac GTPase-activating protein) (GC-GAP) (GTPase regulator interacting with TrkA) (Rho-type GTPase-activating protein 32) (Rho/Cdc42/Rac GTPase-activating protein RICS) (RhoGAP involved in the beta-catenin-N-cadherin and NMDA receptor signaling) (p200RhoGAP) (p250GAP)
Gene: ARHGAP32

Interactor 2: EPHA6 (Q9UF33)
Ephrin type-A receptor 6 (EC 2.7.10.1) (EPH homology kinase 2) (EHK-2) (EPH-like kinase 12) (EK12)
Gene: EPHA6

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PK_Tyr_Ser-Thr~SH3_9
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2087 Hs			1 1036
+	Hs
		64660 RHG32_HUMAN (1-2087): 0: 1424: 100.00		EPHB2_HUMAN (34-1036): 0: 1138: 51.33
+	Hs
		64659 RHG32_HUMAN (1-2087): 0: 1424: 100.00		EPHA2_HUMAN (6-1036): 0: 1046: 45.57
+	Hs
		64642 RHG32_HUMAN (1-2087): 0: 1424: 100.00		FYN_HUMAN (625-931): 3.77e-59: 214: 37.99
+	Hs
		64648 RHG32_HUMAN (1-2087): 0: 1424: 100.00		SRC_HUMAN (623-931): 3.42e-59: 214: 40.32
+	Hs
		253355 SRGP2_HUMAN (191-939): 6.03e-73: 268: 16.21		EPHA7_HUMAN (9-1036): 0: 1192: 55.53
+	Mm
		975149 CHIN_MOUSE (367-567): 7.2e-77: 265: 33.17		EPHA4_MOUSE (15-1036): 0: 1174: 57.07
+	Hs
		253317 SRGP2_HUMAN (191-939): 6.03e-73: 268: 16.21		EPHB2_HUMAN (34-1036): 0: 1138: 51.33
+	Hs
		253307 SRGP2_HUMAN (191-939): 6.03e-73: 268: 16.21		FGFR1_HUMAN (329-968): 6.7e-154: 478: 19.36
+	Hs
		508041 RHG29_HUMAN (134-911): 5.44e-66: 249: 11.78		FGFR1_HUMAN (329-968): 6.7e-154: 478: 19.36
+	Hs
		507972 ABR_HUMAN (350-569): 2.79e-66: 245: 32.89		FGFR1_HUMAN (329-968): 6.7e-154: 478: 19.36
+	Hs
		507962 RHG01_HUMAN (188-572): 1.29e-69: 243: 18.09		FGFR1_HUMAN (329-968): 6.7e-154: 478: 19.36
+	Hs
		435622 RHG01_HUMAN (188-572): 1.29e-69: 243: 18.09		IGF1R_HUMAN (388-932): 8.62e-131: 431: 26.92
+	Hs
		147859 RHG33_HUMAN (74-1276): 2.2e-113: 395: 30.98		FYN_HUMAN (625-931): 3.77e-59: 214: 37.99
+	Hs
		523026 RHG17_HUMAN (189-1018): 1.7e-69: 255: 14.81		SRC_HUMAN (623-931): 3.42e-59: 214: 40.32
+	Hs
		983690 RHG26_HUMAN (64-655): 9.1e-67: 245: 17.69		FAK1_HUMAN (608-939): 4.26e-59: 223: 36.45
+	Hs
		522938 RHG01_HUMAN (188-572): 1.29e-69: 243: 18.09		SRC_HUMAN (623-931): 3.42e-59: 214: 40.32
+	Ce
		220207 TG325_CAEEL (321-566): 1.2e-63: 236: 29.04		SRC2_CAEEL (625-933): 5.82e-60: 216: 36.98
+	Hs
		433324 OCRL_HUMAN (86-552): 4.57e-62: 233: 14.14		YES_HUMAN (623-931): 5.59e-60: 217: 40.65
+	Hs
		523225 3BP1_HUMAN (368-686): 4.12e-64: 235: 25.94		SRC_HUMAN (623-931): 3.42e-59: 214: 40.32
+	Hs
		412137 OCRL_HUMAN (86-552): 4.57e-62: 233: 14.14		FYN_HUMAN (625-931): 3.77e-59: 214: 37.99