Interactor 1: MK03 (P27361)
Mitogen-activated protein kinase 3 (MAP kinase 3) (MAPK 3) (EC 2.7.11.24) (ERT2) (Extracellular signal-regulated kinase 1) (ERK-1) (Insulin-stimulated MAP2 kinase) (MAP kinase isoform p44) (p44-MAPK) (Microtubule-associated protein 2 kinase) (p44-ERK1)
Gene: MAPK3
Interactor 2: PEA15 (Q15121)
Astrocytic phosphoprotein PEA-15 (15 kDa phosphoprotein enriched in astrocytes) (Phosphoprotein enriched in diabetes) (PED)
Gene: PEA15
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.86 | 1.00 | 0.928 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 11702783, 33961781, 32296183, 21900206, unassigned1304 |
| Identification Methods | two hybrid, affinity chromatography technology, two hybrid prey pooling approach, two hybrid array, anti tag coimmunoprecipitation, validated two hybrid |
| Interaction Type | direct interaction, physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | DED~Pkinase |
| Common GO terms | GO:0000165 - MAPK cascade GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0006915 - apoptotic process |
| Homologous interactions | 4 |
Homologous interactions
Color coding for hit scores 
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Last updated: 15 Jul 2024
