HitPredict

Interactor 1: ARP2 (A7MB62)
Actin-related protein 2 (Actin-like protein 2)
Gene: ACTR2

Interactor 2: WASL (Q95107)
Actin nucleation-promoting factor WASL (Neural Wiskott-Aldrich syndrome protein) (N-WASP)
Gene: WASL

Species: Bos taurus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.54	1.00	0.737

Property	Details
Experiments	10219243, 10995436
Identification Methods	pull down
Interaction Type	association, physical association

Property	Details
Interacting Pfam domains	Actin~WH2
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 394 Bt			1 505
+	Hs
		790655 ARP2_HUMAN (1-394): 0: 815: 100.00		WASP_HUMAN (16-487): 1.15e-38: 149: 40.63
+	Hs
		126929 ARP2_HUMAN (1-394): 0: 815: 100.00		WASL_HUMAN (393-498): 3.65e-18: 89: 93.40
+	Ce
		862522 ARP2_CAEEL (1-391): 0: 661: 76.08		Q17795_CAEEL (1-457): 6.23e-38: 148: 24.32
+	Sc
		887724 ACT_YEAST (1-387): 0: 565: 45.74		LAS17_YEAST (21-377): 9.67e-35: 139: 23.43
+	Sc
		689396 ARP2_YEAST (9-390): 0: 549: 67.89		LAS17_YEAST (21-377): 9.67e-35: 139: 23.43
+	Hs
		126926 ACTB_HUMAN (1-388): 0: 574: 46.65		WASL_HUMAN (393-498): 3.65e-18: 89: 93.40
+	Hs
		203220 ACTC_HUMAN (2-388): 0: 569: 46.51		SYNJ1_HUMAN (53-489): 2.61e-19: 94: 11.84
+	Hs
		126931 ACTG_HUMAN (3-388): 0: 573: 46.37		WASL_HUMAN (393-498): 3.65e-18: 89: 93.40
+	Sp
		193726 ACT_SCHPO (3-388): 0: 565: 45.60		WSP1_SCHPO (18-489): 1.15e-19: 94: 17.05
+	Hs
		126932 ACTC_HUMAN (2-388): 0: 569: 46.51		WASL_HUMAN (393-498): 3.65e-18: 89: 93.40
+	Sp
		193732 ARP2_SCHPO (9-390): 0: 537: 66.23		WSP1_SCHPO (18-489): 1.15e-19: 94: 17.05
+	Hs
		554290 ACTA_HUMAN (3-388): 0: 567: 45.86		MUC1_HUMAN (190-484): 6.51e-09: 60.9: 12.75