HitPredict

Interactor 1: MARK3 (P27448)
MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1) (C-TAK1) (cTAK1) (Cdc25C-associated protein kinase 1) (ELKL motif kinase 2) (EMK-2) (Protein kinase STK10) (Ser/Thr protein kinase PAR-1) (Par-1a) (Serine/threonine-protein kinase p78)
Gene: MARK3

Interactor 2: ARHG2 (Q92974)
Rho guanine nucleotide exchange factor 2 (Guanine nucleotide exchange factor H1) (GEF-H1) (Microtubule-regulated Rho-GEF) (Proliferating cell nucleolar antigen p40)
Gene: ARHGEF2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.69	0.60	0.646

Property	Details
Experiments	29089450, 32707033
Identification Methods	proximity labelling technology, affinity chromatography technology, enzymatic study, pull down
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 753 Hs			1 986
+	Hs
		1183087 MARK2_HUMAN (2-753): 0: 626: 59.90		ARHG2_HUMAN (1-986): 0: 736: 100.00
+	Hs
		1273263 MARK4_HUMAN (1-753): 0: 612: 60.24		ARHG2_HUMAN (1-986): 0: 736: 100.00
+	Hs
		647880 MARK3_HUMAN (1-753): 0: 769: 100.00		AKP13_HUMAN (37-964): 2.77e-144: 478: 35.95