HitPredict

Interactor 1: MARK3 (P27448)
MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1) (C-TAK1) (cTAK1) (Cdc25C-associated protein kinase 1) (ELKL motif kinase 2) (EMK-2) (Protein kinase STK10) (Ser/Thr protein kinase PAR-1) (Par-1a) (Serine/threonine-protein kinase p78)
Gene: MARK3

Interactor 2: AGO4 (Q9HCK5)
Protein argonaute-4 (Argonaute4) (hAgo4) (Argonaute RISC catalytic component 4) (Eukaryotic translation initiation factor 2C 4) (eIF-2C 4) (eIF2C 4)
Gene: AGO4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36736316
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 753 Hs			1 861
+	Hs
		647978 MARK3_HUMAN (1-753): 0: 769: 100.00		AGO1_HUMAN (8-861): 0: 1157: 83.49
+	Hs
		647977 MARK3_HUMAN (1-753): 0: 769: 100.00		AGO2_HUMAN (12-861): 0: 1151: 78.94
+	Hs
		647963 MARK3_HUMAN (1-753): 0: 769: 100.00		AGO3_HUMAN (5-861): 0: 1146: 81.18
+	Hs
		1183128 MARK2_HUMAN (2-753): 0: 626: 59.90		AGO4_HUMAN (1-861): 0: 1180: 100.00
+	Hs
		1336279 MARK1_HUMAN (1-753): 0: 619: 62.89		AGO4_HUMAN (1-861): 0: 1180: 100.00
+	Hs
		1183145 MARK2_HUMAN (2-753): 0: 626: 59.90		AGO1_HUMAN (8-861): 0: 1157: 83.49
+	Hs
		1183144 MARK2_HUMAN (2-753): 0: 626: 59.90		AGO2_HUMAN (12-861): 0: 1151: 78.94
+	Hs
		1349677 MARK1_HUMAN (1-753): 0: 619: 62.89		AGO1_HUMAN (8-861): 0: 1157: 83.49
+	Hs
		1183124 MARK2_HUMAN (2-753): 0: 626: 59.90		AGO3_HUMAN (5-861): 0: 1146: 81.18
+	Hs
		1349676 MARK1_HUMAN (1-753): 0: 619: 62.89		AGO2_HUMAN (12-861): 0: 1151: 78.94
+	Hs
		1334282 MARK1_HUMAN (1-753): 0: 619: 62.89		AGO3_HUMAN (5-861): 0: 1146: 81.18