HitPredict

Interactor 1: MARK3 (P27448)
MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1) (C-TAK1) (cTAK1) (Cdc25C-associated protein kinase 1) (ELKL motif kinase 2) (EMK-2) (Protein kinase STK10) (Ser/Thr protein kinase PAR-1) (Par-1a) (Serine/threonine-protein kinase p78)
Gene: MARK3

Interactor 2: TPX2 (Q9ULW0)
Targeting protein for Xklp2 (Differentially expressed in cancerous and non-cancerous lung cells 2) (DIL-2) (Hepatocellular carcinoma-associated antigen 519) (Hepatocellular carcinoma-associated antigen 90) (Protein fls353) (Restricted expression proliferation-associated protein 100) (p100)
Gene: TPX2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	36736316
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Aurora-A_bind~Pkinase
Common GO terms	GO:0005829 - cytosol
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1 753 Hs			1 747
+	Hs
		1183147 MARK2_HUMAN (2-753): 0: 626: 59.90		TPX2_HUMAN (1-747): 2.4e-154: 468: 100.00
+	Hs
		1349679 MARK1_HUMAN (1-753): 0: 619: 62.89		TPX2_HUMAN (1-747): 2.4e-154: 468: 100.00