HitPredict

Interactor 1: VATL (P27449)
V-type proton ATPase 16 kDa proteolipid subunit c (V-ATPase 16 kDa proteolipid subunit c) (Vacuolar proton pump 16 kDa proteolipid subunit c)
Gene: ATP6V0C

Interactor 2: VA0D1 (P61421)
V-type proton ATPase subunit d 1 (V-ATPase subunit d 1) (32 kDa accessory protein) (V-ATPase 40 kDa accessory protein) (V-ATPase AC39 subunit) (p39) (Vacuolar proton pump subunit d 1)
Gene: ATP6V0D1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.74 1.00 0.861

The method score is based on:

Property Details
Experiments 28514442, 33961781, 35271311
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains ATP-synt_C~vATP-synt_AC39
Common GO terms GO:0000220 - vacuolar proton-transporting V-type ATPase, V0 domain
GO:0005765 - lysosomal membrane
GO:0007035 - vacuolar acidification
GO:0010008 - endosome membrane
GO:0016020 - membrane
and 8 others

more...
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 155
Hs

1 351
+ Hs
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024