Interactor 1: VATL (P27449)
V-type proton ATPase 16 kDa proteolipid subunit c (V-ATPase 16 kDa proteolipid subunit c) (Vacuolar proton pump 16 kDa proteolipid subunit c)
Gene: ATP6V0C

Interactor 2: VPP3 (Q13488)
V-type proton ATPase 116 kDa subunit a 3 (V-ATPase 116 kDa subunit a 3) (Osteoclastic proton pump 116 kDa subunit) (OC-116 kDa) (OC116) (T-cell immune regulator 1) (T-cell immune response cDNA7 protein) (TIRC7) (Vacuolar proton translocating ATPase 116 kDa subunit a isoform 3)
Gene: TCIRG1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.691

The method score is based on:

Property Details
Experiments 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains ATP-synt_C~V_ATPase_I
Common GO terms GO:0000220 - vacuolar proton-transporting V-type ATPase, V0 domain
GO:0005765 - lysosomal membrane
GO:0005886 - plasma membrane
GO:0007035 - vacuolar acidification
GO:0007042 - lysosomal lumen acidification
and 6 others

more...

Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 155
Hs

1 830
+ Hs
+ Hs
+ Hs
+ Sc
+ Sc
+ Sc
+ Sc
+ Sc
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024