HitPredict

Interactor 1: ARNT (P27540)
Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Class E basic helix-loop-helix protein 2) (bHLHe2) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1-beta) (HIF-1-beta) (HIF1-beta)
Gene: ARNT

Interactor 2: CUL2 (Q13617)
Cullin-2 (CUL-2)
Gene: CUL2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	24981860, 20049704
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 789 Hs			1 745
+	Hs
		649103 ARNT_HUMAN (1-789): 0: 649: 100.00		CUL4A_HUMAN (4-745): 0: 773: 26.86
+	Hs
		1041447 EPAS1_HUMAN (76-771): 3.47e-132: 415: 16.85		CUL2_HUMAN (1-745): 0: 840: 100.00
+	Hs
		1041339 HIF1A_HUMAN (82-787): 5.9e-129: 406: 17.48		CUL2_HUMAN (1-745): 0: 840: 100.00
+	Hs
		126128 BMAL1_HUMAN (39-622): 1.71e-150: 456: 31.74		CUL1_HUMAN (6-745): 0: 775: 36.24
+	Rn
		88863 HIF1A_RAT (74-788): 3.74e-130: 409: 16.58		D4A0H4_RAT (1-745): 0: 813: 94.90
+	Hs
		728914 AHR_HUMAN (64-767): 5.39e-93: 311: 14.89		CUL4B_HUMAN (4-745): 0: 771: 27.79
+	Hs
		728913 AHR_HUMAN (64-767): 5.39e-93: 311: 14.89		CUL3_HUMAN (1-745): 0: 768: 26.38