HitPredict

Interactor 1: CDC15 (P27636)
Cell division control protein 15 (EC 2.7.11.1)
Gene: CDC15

Interactor 2: KOG1 (P38873)
Target of rapamycin complex 1 subunit KOG1 (TORC1 subunit KOG1) (Kontroller of growth protein 1) (Local anesthetic-sensitive protein 24) (Regulatory-associated protein of TOR) (Raptor)
Gene: KOG1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	33566094
Identification Methods	protein complementation assay
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	HEAT~Pkinase
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 974 Sc			1 1557
+	Hs
		681935 AKT1_HUMAN (2-334): 5.25e-124: 387: 21.59		RPTOR_HUMAN (20-1552): 0: 1188: 28.59
+	Hs
		117016 SGK1_HUMAN (8-339): 4.21e-118: 370: 27.27		RPTOR_HUMAN (20-1552): 0: 1188: 28.59
+	Rn
		936839 AKT3_RAT (1-329): 3.04e-123: 385: 20.74		STRN_RAT (808-1547): 2.46e-80: 284: 11.79
+	Hs
		215222 STK4_HUMAN (11-280): 3.03e-109: 348: 38.04		STRN_HUMAN (808-1547): 3.37e-81: 287: 11.66
+	Hs
		215226 STK3_HUMAN (11-280): 1.06e-108: 347: 38.41		STRN_HUMAN (808-1547): 3.37e-81: 287: 11.66
+	Hs
		1022811 STK4_HUMAN (11-280): 3.03e-109: 348: 38.04		STRN3_HUMAN (789-1547): 1.17e-79: 283: 9.88
+	Hs
		1022814 STK3_HUMAN (11-280): 1.06e-108: 347: 38.41		STRN3_HUMAN (789-1547): 1.17e-79: 283: 9.88
+	At
		1105348 KIN10_ARATH (24-455): 1.02e-130: 405: 18.28		RTOR1_ARATH (700-1554): 2.97e-40: 165: 10.27
+	At
		955216 KIN11_ARATH (24-448): 2.82e-128: 399: 18.83		RTOR1_ARATH (700-1554): 2.97e-40: 165: 10.27
+	Hs
		863606 AKT3_HUMAN (1-334): 1.05e-124: 388: 20.50		COPA_HUMAN (1199-1484): 2.15e-25: 117: 12.18
+	Dm
		1213428 AKT1_DROME (18-339): 3.17e-122: 387: 21.89		Q9W0B8_DROME (1199-1443): 8.96e-24: 111: 11.55
+	Hs
		863416 STK4_HUMAN (11-280): 3.03e-109: 348: 38.04		COPA_HUMAN (1199-1484): 2.15e-25: 117: 12.18
+	Hs
		131539 STK25_HUMAN (31-305): 7.79e-43: 164: 37.59		STRN_HUMAN (808-1547): 3.37e-81: 287: 11.66
+	Hs
		215296 STK24_HUMAN (31-300): 5.58e-43: 164: 37.18		STRN_HUMAN (808-1547): 3.37e-81: 287: 11.66
+	Hs
		1022891 STK24_HUMAN (31-300): 5.58e-43: 164: 37.18		STRN3_HUMAN (789-1547): 1.17e-79: 283: 9.88
+	Hs
		131567 STK25_HUMAN (31-305): 7.79e-43: 164: 37.59		STRN3_HUMAN (789-1547): 1.17e-79: 283: 9.88
+	Ce
		110183 GCK1_CAEEL (20-288): 8.44e-44: 171: 36.56		COPB2_CAEEL (1198-1507): 9.88e-65: 241: 14.10
+	Ce
		106564 GCK1_CAEEL (20-288): 8.44e-44: 171: 36.56		G5EE12_CAEEL (1194-1547): 1.52e-63: 232: 16.08