Interactor 1: SIN3 (P22579)
Transcriptional regulatory protein SIN3
Gene: SIN3

Interactor 2: UME6 (P39001)
Transcriptional regulatory protein UME6 (Negative transcriptional regulator of IME2) (Regulator of inducer of meiosis protein 16) (Unscheduled meiotic gene expression protein 6)
Gene: UME6

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.89 0.55 0.702

The method score is based on:

Property Details
Experiments 9150136, 36854981, 11238941, 16314178, 38886580, 21179020
Identification Methods affinity chromatography technology, two hybrid, pull down, proximity labelling technology, tandem affinity purification
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0005634 - nucleus
GO:0033698 - Rpd3L complex
GO:0045944 - positive regulation of transcription by RNA polymerase II
GO:0051321 - meiotic cell cycle
and 1 others

more...

Homologous interactions 0

Service provided by Combinatics, Japan

Last updated: 11Aug2025