HitPredict

Interactor 1: P121C (A8CG34)
Nuclear envelope pore membrane protein POM 121C (Nuclear pore membrane protein 121-2) (POM121-2) (Pore membrane protein of 121 kDa C)
Gene: POM121C

Interactor 2: SEH1 (Q96EE3)
Nucleoporin SEH1 (GATOR2 complex protein SEH1) (Nup107-160 subcomplex subunit SEH1) (SEC13-like protein)
Gene: SEH1L

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	26496610
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005635 - nuclear envelope GO:0005643 - nuclear pore GO:0051028 - mRNA transport
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1229 Hs			1 360
+	Hs
		1288235 P121A_HUMAN (1-1229): 8.01e-79: 286: 93.69		SNR40_HUMAN (3-140): 3.35e-22: 98: 18.88
+	Hs
		878229 P121A_HUMAN (1-1229): 8.01e-79: 286: 93.69		SEC13_HUMAN (216-346): 5.58e-17: 82.6: 18.80
+	Hs
		72755 B4DET5_HUMAN (5-742): 3.52e-12: 72.9: 9.72		SEH1_HUMAN (1-360): 1.71e-77: 243: 100.00
+	Hs
		727302 NU214_HUMAN (91-936): 1.02e-10: 68.8: 10.61		SEH1_HUMAN (1-360): 1.71e-77: 243: 100.00
+	Sc
		774376 NU159_YEAST (793-1199): 1.64e-10: 67.8: 21.05		SEC13_YEAST (7-319): 1.17e-73: 232: 29.84
+	Sc
		758551 SEC31_YEAST (712-1170): 7.21e-10: 65.9: 14.97		SEC13_YEAST (7-319): 1.17e-73: 232: 29.84
+	Hs
		1057782 NCOA6_HUMAN (359-1228): 9.06e-13: 75.3: 9.95		FBXW7_HUMAN (3-246): 5.14e-41: 154: 14.34
+	Hs
		1056932 MDC1_HUMAN (80-893): 2.1e-29: 129: 10.92		SNR40_HUMAN (3-140): 3.35e-22: 98: 18.88
+	Hs
		1219809 ANKH1_HUMAN (453-1171): 3.1e-11: 70.5: 15.06		FBXW7_HUMAN (3-246): 5.14e-41: 154: 14.34
+	Hs
		1281391 PRR36_HUMAN (3-580): 1.7e-10: 67.9: 9.78		FBXW7_HUMAN (3-246): 5.14e-41: 154: 14.34
+	Dm
		1370295 Q9VLS7_DROME (3-859): 2e-15: 84.1: 9.65		POC1_DROME (9-309): 3.76e-33: 128: 19.60
+	Hs
		1302927 MINT_HUMAN (1-1187): 3.89e-14: 80.1: 9.85		NLE1_HUMAN (210-358): 6.14e-32: 126: 15.58
+	Hs
		1244287 ARI1B_HUMAN (129-1213): 3.55e-15: 83.3: 9.44		SNR40_HUMAN (3-140): 3.35e-22: 98: 18.88
+	Dm
		1358850 NUP98_DROME (626-1155): 8.76e-19: 95.1: 18.43		WDS_DROME (265-360): 3.21e-17: 83.7: 16.67
+	Hs
		1288258 MINT_HUMAN (1-1187): 3.89e-14: 80.1: 9.85		SNR40_HUMAN (3-140): 3.35e-22: 98: 18.88
+	Hs
		72754 B4DET5_HUMAN (5-742): 3.52e-12: 72.9: 9.72		SNR40_HUMAN (3-140): 3.35e-22: 98: 18.88
+	Hs
		903229 NCOA6_HUMAN (359-1228): 9.06e-13: 75.3: 9.95		WDR5_HUMAN (253-360): 5.88e-19: 88.4: 18.52
+	Hs
		903354 ANKH1_HUMAN (453-1171): 3.1e-11: 70.5: 15.06		WDR5_HUMAN (253-360): 5.88e-19: 88.4: 18.52
+	Hs
		857954 NUP98_HUMAN (784-1215): 1.89e-09: 64.3: 20.76		SEC13_HUMAN (216-346): 5.58e-17: 82.6: 18.80
+	Sc
		774364 NU159_YEAST (793-1199): 1.64e-10: 67.8: 21.05		SEH1_YEAST (185-338): 3.3e-10: 62.7: 16.05