HitPredict

Interactor 1: RFA1 (P27694)
Replication protein A 70 kDa DNA-binding subunit (RP-A p70) (Replication factor A protein 1) (RF-A protein 1) (Single-stranded DNA-binding protein) [Cleaved into: Replication protein A 70 kDa DNA-binding subunit, N-terminally processed]
Gene: RPA1

Interactor 2: RFC4 (P35249)
Replication factor C subunit 4 (Activator 1 37 kDa subunit) (A1 37 kDa subunit) (Activator 1 subunit 4) (Replication factor C 37 kDa subunit) (RF-C 37 kDa subunit) (RFC37)
Gene: RFC4

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	26474068, 37827155, 24332808
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006261 - DNA-templated DNA replication GO:0006281 - DNA repair
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 616 Hs			1 363
+	Hs
		650502 RFA1_HUMAN (1-616): 0: 781: 100.00		RFC2_HUMAN (1-358): 8.75e-87: 267: 33.80
+	Hs
		650557 RFA1_HUMAN (1-616): 0: 781: 100.00		RFC5_HUMAN (28-356): 5.29e-81: 252: 36.67
+	Hs
		650558 RFA1_HUMAN (1-616): 0: 781: 100.00		RFC3_HUMAN (39-361): 1.07e-66: 216: 24.28