HitPredict

Interactor 1: RFA1 (P27694)
Replication protein A 70 kDa DNA-binding subunit (RP-A p70) (Replication factor A protein 1) (RF-A protein 1) (Single-stranded DNA-binding protein) [Cleaved into: Replication protein A 70 kDa DNA-binding subunit, N-terminally processed]
Gene: RPA1

Interactor 2: DHX9 (Q08211)
ATP-dependent RNA helicase A (EC 3.6.4.13) (DEAH box protein 9) (DExH-box helicase 9) (Leukophysin) (LKP) (Nuclear DNA helicase II) (NDH II) (RNA helicase A)
Gene: DHX9

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	37827155, 24332808
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003697 - single-stranded DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006260 - DNA replication GO:0046872 - metal ion binding
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 616 Hs			1 1270
+	Hs
		652224 RFA1_HUMAN (1-616): 0: 781: 100.00		DHX36_HUMAN (258-1158): 0: 820: 32.70
+	Hs
		651200 RFA1_HUMAN (1-616): 0: 781: 100.00		DHX8_HUMAN (51-1122): 0: 810: 20.54
+	Hs
		224758 RFA1_HUMAN (1-616): 0: 781: 100.00		DHX16_HUMAN (117-1103): 0: 806: 21.77
+	Hs
		651836 RFA1_HUMAN (1-616): 0: 781: 100.00		PRP16_HUMAN (35-1090): 0: 787: 21.40
+	Hs
		651559 RFA1_HUMAN (1-616): 0: 781: 100.00		DHX29_HUMAN (249-1143): 0: 768: 30.91
+	Hs
		651469 RFA1_HUMAN (1-616): 0: 781: 100.00		DHX57_HUMAN (99-1142): 0: 765: 28.74
+	Hs
		195347 RFA1_HUMAN (1-616): 0: 781: 100.00		DHX15_HUMAN (361-1076): 0: 742: 25.00
+	Hs
		651534 RFA1_HUMAN (1-616): 0: 781: 100.00		DHX30_HUMAN (381-1093): 3.3e-123: 412: 33.96
+	Hs
		652254 RFA1_HUMAN (1-616): 0: 781: 100.00		YTDC2_HUMAN (385-584): 2.01e-51: 201: 48.77