HitPredict

Interactor 1: RFA1 (P27694)
Replication protein A 70 kDa DNA-binding subunit (RP-A p70) (Replication factor A protein 1) (RF-A protein 1) (Single-stranded DNA-binding protein) [Cleaved into: Replication protein A 70 kDa DNA-binding subunit, N-terminally processed]
Gene: RPA1

Interactor 2: EP300 (Q09472)
Histone acetyltransferase p300 (p300 HAT) (EC 2.3.1.48) (E1A-associated protein p300) (Histone butyryltransferase p300) (EC 2.3.1.-) (Histone crotonyltransferase p300) (EC 2.3.1.-) (Protein 2-hydroxyisobutyryltransferase p300) (EC 2.3.1.-) (Protein lactyltransferas p300) (EC 2.3.1.-) (Protein propionyltransferase p300) (EC 2.3.1.-)
Gene: EP300

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	30110629
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003684 - damaged DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 616 Hs			1 2414
+	Hs
		652353 RFA1_HUMAN (1-616): 0: 781: 100.00		BAZ1A_HUMAN (889-1176): 3.58e-51: 202: 21.31
+	Hs
		652613 RFA1_HUMAN (1-616): 0: 781: 100.00		TRI33_HUMAN (604-1201): 1.37e-44: 180: 14.50
+	Hs
		651064 RFA1_HUMAN (1-616): 0: 781: 100.00		BPTF_HUMAN (2011-2413): 1.11e-14: 82.9: 12.86
+	Hs
		651208 RFA1_HUMAN (1-616): 0: 781: 100.00		MDC1_HUMAN (455-1061): 8.69e-13: 76.6: 11.82
+	Hs
		651796 RFA1_HUMAN (1-616): 0: 781: 100.00		PHIP_HUMAN (1068-1157): 6.78e-12: 73.6: 42.86
+	Hs
		651725 RFA1_HUMAN (1-616): 0: 781: 100.00		KMT2C_HUMAN (416-1078): 1.02e-10: 70.1: 11.13
+	Sc
		607253 RFA1_YEAST (4-615): 0: 596: 31.69		BDF1_YEAST (1041-1152): 6.84e-09: 63.2: 37.61
+	Hs
		1056865 RADX_HUMAN (27-384): 6.8e-66: 233: 16.24		MDC1_HUMAN (455-1061): 8.69e-13: 76.6: 11.82