Interactor 1: RFA1 (P27694)
Replication protein A 70 kDa DNA-binding subunit (RP-A p70) (Replication factor A protein 1) (RF-A protein 1) (Single-stranded DNA-binding protein) [Cleaved into: Replication protein A 70 kDa DNA-binding subunit, N-terminally processed]
Gene: RPA1

Interactor 2: ATM (Q13315)
Serine-protein kinase ATM (EC 2.7.11.1) (Ataxia telangiectasia mutated) (A-T mutated)
Gene: ATM

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.73 0.60 0.664

The method score is based on:

Property Details
Experiments 12641457, 9725899, 10713094
Identification Methods pull down, enzymatic study
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000723 - telomere maintenance
GO:0000724 - double-strand break repair via homologous recombination
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006974 - DNA damage response
and 1 others

more...

Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 616
Hs

1 3056
+ Hs
+ Hs
+ Hs
+ Sc
+ Hs
+ Sc
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024