HitPredict

Interactor 1: RFA1 (P27694)
Replication protein A 70 kDa DNA-binding subunit (RP-A p70) (Replication factor A protein 1) (RF-A protein 1) (Single-stranded DNA-binding protein) [Cleaved into: Replication protein A 70 kDa DNA-binding subunit, N-terminally processed]
Gene: RPA1

Interactor 2: DYR1A (Q13627)
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (EC 2.7.11.23) (EC 2.7.12.1) (Dual specificity YAK1-related kinase) (HP86) (Protein kinase minibrain homolog) (MNBH) (hMNB)
Gene: DYRK1A

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	36950384
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 616 Hs			1 763
+	Hs
		647830 RFA1_HUMAN (1-616): 0: 781: 100.00		MARK3_HUMAN (105-758): 1.17e-123: 389: 17.72
+	Hs
		651838 RFA1_HUMAN (1-616): 0: 781: 100.00		DYRK2_HUMAN (46-549): 5.03e-120: 375: 33.53
+	Hs
		414753 RFA1_HUMAN (1-616): 0: 781: 100.00		CDK1_HUMAN (156-482): 1.29e-121: 368: 26.57
+	Hs
		650466 RFA1_HUMAN (1-616): 0: 781: 100.00		AKT1_HUMAN (38-466): 4.44e-117: 363: 19.42
+	Hs
		625131 RFA1_HUMAN (1-616): 0: 781: 100.00		CDK2_HUMAN (156-420): 1.05e-117: 358: 26.85