HitPredict

Interactor 1: RFA1 (P27694)
Replication protein A 70 kDa DNA-binding subunit (RP-A p70) (Replication factor A protein 1) (RF-A protein 1) (Single-stranded DNA-binding protein) [Cleaved into: Replication protein A 70 kDa DNA-binding subunit, N-terminally processed]
Gene: RPA1

Interactor 2: RIF1 (Q5UIP0)
Telomere-associated protein RIF1 (Rap1-interacting factor 1 homolog)
Gene: RIF1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	37827155, 20711169
Identification Methods	proximity labelling technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000723 - telomere maintenance GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006281 - DNA repair GO:0006974 - DNA damage response and 1 others more... GO:0035861 - site of double-strand break
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 616 Hs			1 2472
+	Hs
		651569 RFA1_HUMAN (1-616): 0: 781: 100.00		RBBP6_HUMAN (1213-2173): 1.39e-26: 122: 9.31
+	Hs
		651461 RFA1_HUMAN (1-616): 0: 781: 100.00		NIPBL_HUMAN (948-1837): 3.15e-19: 98.1: 12.40
+	Hs
		650614 RFA1_HUMAN (1-616): 0: 781: 100.00		MAP1B_HUMAN (745-2457): 3e-18: 94.6: 8.05
+	Hs
		652037 RFA1_HUMAN (1-616): 0: 781: 100.00		MINT_HUMAN (779-2447): 5.2e-18: 94.2: 7.95
+	Hs
		651208 RFA1_HUMAN (1-616): 0: 781: 100.00		MDC1_HUMAN (958-2272): 4.95e-18: 93.9: 10.74
+	Hs
		60149 RFA1_HUMAN (1-616): 0: 781: 100.00		XIRP2_HUMAN (983-2380): 1.01e-11: 73.4: 8.38
+	Hs
		1056865 RADX_HUMAN (27-384): 6.8e-66: 233: 16.24		MDC1_HUMAN (958-2272): 4.95e-18: 93.9: 10.74