HitPredict

Interactor 1: RFA1 (P27694)
Replication protein A 70 kDa DNA-binding subunit (RP-A p70) (Replication factor A protein 1) (RF-A protein 1) (Single-stranded DNA-binding protein) [Cleaved into: Replication protein A 70 kDa DNA-binding subunit, N-terminally processed]
Gene: RPA1

Interactor 2: WDR76 (Q9H967)
WD repeat-containing protein 76
Gene: WDR76

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	27248496, 31353912
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0006974 - DNA damage response GO:0090734 - site of DNA damage
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 616 Hs			1 626
+	Hs
		652407 RFA1_HUMAN (1-616): 0: 781: 100.00		NLE1_HUMAN (181-575): 1.3e-63: 219: 12.70
+	Hs
		650859 RFA1_HUMAN (1-616): 0: 781: 100.00		WDR5_HUMAN (435-622): 2.2e-42: 157: 12.23
+	Hs
		651925 RFA1_HUMAN (1-616): 0: 781: 100.00		SNR40_HUMAN (440-625): 1.07e-33: 134: 11.83
+	Hs
		651049 RFA1_HUMAN (1-616): 0: 781: 100.00		RBBP4_HUMAN (233-477): 2.84e-19: 92.6: 14.55
+	Sc
		607371 RFA1_YEAST (4-615): 0: 596: 31.69		CMR1_YEAST (159-623): 1.38e-74: 249: 23.50