HitPredict

Interactor 1: RFA1 (P27694)
Replication protein A 70 kDa DNA-binding subunit (RP-A p70) (Replication factor A protein 1) (RF-A protein 1) (Single-stranded DNA-binding protein) [Cleaved into: Replication protein A 70 kDa DNA-binding subunit, N-terminally processed]
Gene: RPA1

Interactor 2: H2AW (Q9P0M6)
Core histone macro-H2A.2 (Histone macroH2A2) (mH2A2)
Gene: MACROH2A2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	37827155
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000781 - chromosome, telomeric region GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 616 Hs			1 372
+	Hs
		260761 RFA1_HUMAN (1-616): 0: 781: 100.00		H2AY_HUMAN (1-371): 8.19e-156: 444: 66.31
+	Hs
		652082 RFA1_HUMAN (1-616): 0: 781: 100.00		MACD1_HUMAN (167-371): 4.34e-68: 219: 19.71
+	Hs
		555303 RFA1_HUMAN (1-616): 0: 781: 100.00		H2AX_HUMAN (1-144): 1.72e-66: 208: 57.14
+	Hs
		651615 RFA1_HUMAN (1-616): 0: 781: 100.00		H2A2B_HUMAN (1-123): 1.24e-64: 203: 63.49
+	Hs
		391559 RFA1_HUMAN (1-616): 0: 781: 100.00		H2A1B_HUMAN (1-126): 6.65e-64: 201: 60.47
+	Hs
		651357 RFA1_HUMAN (1-616): 0: 781: 100.00		PAR14_HUMAN (152-370): 1.01e-20: 96: 18.27
+	Sc
		392055 RFA1_YEAST (4-615): 0: 596: 31.69		H2A1_YEAST (14-125): 3.15e-41: 143: 65.79
+	Sc
		392299 RFA1_YEAST (4-615): 0: 596: 31.69		H2A2_YEAST (14-124): 2.55e-41: 143: 65.77