HitPredict

Interactor 1: RFA1 (P27694)
Replication protein A 70 kDa DNA-binding subunit (RP-A p70) (Replication factor A protein 1) (RF-A protein 1) (Single-stranded DNA-binding protein) [Cleaved into: Replication protein A 70 kDa DNA-binding subunit, N-terminally processed]
Gene: RPA1

Interactor 2: KS6A6 (Q9UK32)
Ribosomal protein S6 kinase alpha-6 (S6K-alpha-6) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 6) (p90-RSK 6) (p90RSK6) (Ribosomal S6 kinase 4) (RSK-4) (pp90RSK4)
Gene: RPS6KA6

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	37827155
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 616 Hs			1 745
+	Hs
		650723 RFA1_HUMAN (1-616): 0: 781: 100.00		KS6A3_HUMAN (2-745): 0: 806: 76.54
+	Hs
		651283 RFA1_HUMAN (1-616): 0: 781: 100.00		KS6A1_HUMAN (2-743): 0: 786: 71.54
+	Hs
		270375 RFA1_HUMAN (1-616): 0: 781: 100.00		KS6A5_HUMAN (52-739): 0: 708: 41.41
+	Hs
		650467 RFA1_HUMAN (1-616): 0: 781: 100.00		AKT2_HUMAN (423-727): 1.45e-119: 369: 23.98
+	Hs
		650466 RFA1_HUMAN (1-616): 0: 781: 100.00		AKT1_HUMAN (417-742): 1.91e-117: 363: 24.13
+	Hs
		616673 RFA1_HUMAN (1-616): 0: 781: 100.00		KS6B1_HUMAN (401-738): 7.06e-111: 348: 23.94
+	Dm
		1097973 RFA1_DROME (1-614): 0: 619: 41.00		Q94533_DROME (406-702): 9.85e-90: 291: 25.62