HitPredict

Interactor 1: RFA1 (P27694)
Replication protein A 70 kDa DNA-binding subunit (RP-A p70) (Replication factor A protein 1) (RF-A protein 1) (Single-stranded DNA-binding protein) [Cleaved into: Replication protein A 70 kDa DNA-binding subunit, N-terminally processed]
Gene: RPA1

Interactor 2: M4K5 (Q9Y4K4)
Mitogen-activated protein kinase kinase kinase kinase 5 (EC 2.7.11.1) (Kinase homologous to SPS1/STE20) (KHS) (MAPK/ERK kinase kinase kinase 5) (MEK kinase kinase 5) (MEKKK 5)
Gene: MAP4K5

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	37827155
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 616 Hs			1 846
+	Hs
		651140 RFA1_HUMAN (1-616): 0: 781: 100.00		KCC2D_HUMAN (8-517): 1.77e-144: 437: 18.38
+	Hs
		647830 RFA1_HUMAN (1-616): 0: 781: 100.00		MARK3_HUMAN (13-559): 3.08e-135: 422: 18.71
+	Hs
		650467 RFA1_HUMAN (1-616): 0: 781: 100.00		AKT2_HUMAN (1-350): 8.02e-130: 398: 22.63
+	Hs
		650466 RFA1_HUMAN (1-616): 0: 781: 100.00		AKT1_HUMAN (12-346): 6.18e-125: 386: 22.38
+	Hs
		652477 RFA1_HUMAN (1-616): 0: 781: 100.00		STK26_HUMAN (7-302): 4.07e-119: 368: 43.43
+	Hs
		652744 RFA1_HUMAN (1-616): 0: 781: 100.00		STK24_HUMAN (8-379): 1.48e-118: 368: 37.53
+	Hs
		652567 RFA1_HUMAN (1-616): 0: 781: 100.00		TNIK_HUMAN (14-295): 1.26e-72: 262: 45.73
+	Hs
		324740 RFA1_HUMAN (1-616): 0: 781: 100.00		M4K4_HUMAN (2-295): 4.04e-64: 236: 43.51
+	Zm
		2187 A0A1D6EZA2_MAIZE (83-505): 1.89e-78: 267: 14.57		A0A0B4J3D8_MAIZE (8-362): 3.29e-124: 383: 23.61