Interactor 1: APEX1 (P27695)
DNA repair nuclease/redox regulator APEX1 (EC 3.1.11.2) (EC 3.1.21.-) (APEX nuclease) (APEN) (Apurinic-apyrimidinic endonuclease 1) (AP endonuclease 1) (APE-1) (DNA-(apurinic or apyrimidinic site) endonuclease) (Redox factor-1) (REF-1) [Cleaved into: DNA repair nuclease/redox regulator APEX1, mitochondrial]
Gene: APEX1

Interactor 2: MUTYH (Q9UIF7)
Adenine DNA glycosylase (EC 3.2.2.31) (MutY homolog) (hMYH)
Gene: MUTYH

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.74 0.60 0.670

The method score is based on:

Property Details
Experiments 24209961, 11092888, 19820168
Identification Methods unspecified method, affinity chromatography technology, pull down
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005739 - mitochondrion
GO:0006281 - DNA repair
GO:0006284 - base-excision repair
and 1 others

more...

Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 318
Hs

1 546
+ Mm
+ Sp
+ At

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024