HitPredict

Interactor 1: CD82 (P27701)
CD82 antigen (C33 antigen) (IA4) (Inducible membrane protein R2) (Metastasis suppressor Kangai-1) (Suppressor of tumorigenicity 6 protein) (Tetraspanin-27) (Tspan-27) (CD antigen CD82)
Gene: CD82

Interactor 2: IGSF8 (Q969P0)
Immunoglobulin superfamily member 8 (IgSF8) (CD81 partner 3) (Glu-Trp-Ile EWI motif-containing protein 2) (EWI-2) (Keratinocytes-associated transmembrane protein 4) (KCT-4) (LIR-D1) (Prostaglandin regulatory-like protein) (PGRL) (CD antigen CD316)
Gene: IGSF8

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	12750295
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 267 Hs			1 613
+	Hs
		905541 TSN5_HUMAN (8-267): 5.13e-65: 205: 26.69		IGSF8_HUMAN (1-613): 5.61e-173: 507: 100.00
+	Hs
		326168 TSN15_HUMAN (9-258): 7.16e-52: 172: 18.90		IGSF8_HUMAN (1-613): 5.61e-173: 507: 100.00
+	Hs
		887922 CD81_HUMAN (4-259): 4.59e-49: 163: 22.52		IGSF8_HUMAN (1-613): 5.61e-173: 507: 100.00
+	Hs
		602274 CD9_HUMAN (2-260): 1.54e-47: 159: 25.19		IGSF8_HUMAN (1-613): 5.61e-173: 507: 100.00
+	Mm
		728559 CD81_MOUSE (4-259): 4.82e-48: 161: 22.90		IGSF8_MOUSE (22-613): 1.44e-171: 503: 90.20
+	Hs
		653105 CD82_HUMAN (1-267): 5.82e-73: 225: 100.00		FPRP_HUMAN (37-604): 5.69e-51: 191: 19.72
+	Hs
		905572 TSN5_HUMAN (8-267): 5.13e-65: 205: 26.69		FPRP_HUMAN (37-604): 5.69e-51: 191: 19.72
+	Hs
		1245273 TSN14_HUMAN (10-258): 8.59e-63: 199: 23.14		FPRP_HUMAN (37-604): 5.69e-51: 191: 19.72
+	Hs
		819474 CD151_HUMAN (3-261): 2.39e-58: 188: 27.48		FPRP_HUMAN (37-604): 5.69e-51: 191: 19.72
+	Hs
		446077 CD63_HUMAN (4-258): 5.91e-54: 176: 24.71		FPRP_HUMAN (37-604): 5.69e-51: 191: 19.72
+	Hs
		326244 TSN15_HUMAN (9-258): 7.16e-52: 172: 18.90		FPRP_HUMAN (37-604): 5.69e-51: 191: 19.72
+	Hs
		887973 CD81_HUMAN (4-259): 4.59e-49: 163: 22.52		FPRP_HUMAN (37-604): 5.69e-51: 191: 19.72
+	Hs
		602290 CD9_HUMAN (2-260): 1.54e-47: 159: 25.19		FPRP_HUMAN (37-604): 5.69e-51: 191: 19.72
+	Hs
		253639 TSN5_HUMAN (8-267): 5.13e-65: 205: 26.69		IGSF3_HUMAN (19-305): 3.84e-20: 97.2: 17.89
+	Hs
		888000 CD81_HUMAN (4-259): 4.59e-49: 163: 22.52		ROBO1_HUMAN (25-507): 1.65e-32: 136: 12.83
+	Hs
		253665 TSN14_HUMAN (10-258): 8.59e-63: 199: 23.14		IGSF3_HUMAN (19-305): 3.84e-20: 97.2: 17.89
+	Hs
		1199563 TSN33_HUMAN (8-266): 1.09e-62: 200: 24.91		TITIN_HUMAN (169-612): 1.96e-12: 72.9: 9.60
+	Hs
		253614 TSN15_HUMAN (9-258): 7.16e-52: 172: 18.90		IGSF3_HUMAN (19-305): 3.84e-20: 97.2: 17.89
+	Hs
		237786 TSN3_HUMAN (1-262): 4.58e-50: 166: 25.10		FGFR2_HUMAN (70-300): 6.05e-20: 96.4: 12.97
+	Hs
		253625 CD9_HUMAN (2-260): 1.54e-47: 159: 25.19		IGSF3_HUMAN (19-305): 3.84e-20: 97.2: 17.89