HitPredict

Interactor 1: PYR1 (P27708)
Multifunctional protein CAD (Carbamoyl phosphate synthetase 2-aspartate transcarbamylase-dihydroorotase) [Includes: Glutamine-dependent carbamoyl phosphate synthase (EC 6.3.5.5); Glutamine amidotransferase (GATase) (GLNase) (EC 3.5.1.2); Ammonium-dependent carbamoyl phosphate synthase (CPS) (CPSase) (EC 6.3.4.16); Aspartate carbamoyltransferase (EC 2.1.3.2); Dihydroorotase (EC 3.5.2.3)]
Gene: CAD

Interactor 2: UBE2H (P62256)
Ubiquitin-conjugating enzyme E2 H (EC 2.3.2.23) ((E3-independent) E2 ubiquitin-conjugating enzyme H) (EC 2.3.2.24) (E2 ubiquitin-conjugating enzyme H) (UbcH2) (Ubiquitin carrier protein H) (Ubiquitin-conjugating enzyme E2-20K) (Ubiquitin-protein ligase H)
Gene: UBE2H

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	38113892
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 2225 Hs			1 183
+	Hs
		679439 CPSM_HUMAN (2-1448): 0: 1504: 50.61		UBE2H_HUMAN (1-183): 8.84e-64: 196: 100.00
+	Hs
		908616 DPYL2_HUMAN (1397-1915): 9.65e-161: 510: 18.29		UBE2H_HUMAN (1-183): 8.84e-64: 196: 100.00
+	Hs
		828998 DPYL1_HUMAN (1397-1915): 3.53e-160: 508: 17.78		UBE2A_HUMAN (4-150): 8.87e-65: 197: 30.46
+	Hs
		908522 DPYL3_HUMAN (1397-1915): 5.83e-160: 507: 18.15		UBE2H_HUMAN (1-183): 8.84e-64: 196: 100.00
+	Hs
		927751 DPYL1_HUMAN (1397-1915): 3.53e-160: 508: 17.78		UBE2B_HUMAN (4-149): 8e-64: 195: 30.67