HitPredict

Interactor 1: PYR1 (P27708)
Multifunctional protein CAD (Carbamoyl phosphate synthetase 2-aspartate transcarbamylase-dihydroorotase) [Includes: Glutamine-dependent carbamoyl phosphate synthase (EC 6.3.5.5); Glutamine amidotransferase (GATase) (GLNase) (EC 3.5.1.2); Ammonium-dependent carbamoyl phosphate synthase (CPS) (CPSase) (EC 6.3.4.16); Aspartate carbamoyltransferase (EC 2.1.3.2); Dihydroorotase (EC 3.5.2.3)]
Gene: CAD

Interactor 2: TNIP1 (Q15025)
TNFAIP3-interacting protein 1 (A20-binding inhibitor of NF-kappa-B activation 1) (ABIN-1) (HIV-1 Nef-interacting protein) (Nef-associated factor 1) (Naf1) (Nip40-1) (Virion-associated nuclear shuttling protein) (VAN) (hVAN)
Gene: TNIP1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36574265
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 2225 Hs			1 636
+	Hs
		653409 PYR1_HUMAN (1-2225): 0: 2858: 100.00		SMC3_HUMAN (278-527): 2.28e-43: 169: 25.09
+	Hs
		148420 PYR1_HUMAN (1-2225): 0: 2858: 100.00		CTRO_HUMAN (51-557): 1.5e-16: 86.2: 14.12
+	Mm
		70571 PYR1_MOUSE (1-2225): 0: 2821: 95.37		FTM_MOUSE (17-526): 3.12e-25: 113: 15.30
+	Hs
		679448 CPSM_HUMAN (2-1448): 0: 1504: 50.61		TNIP1_HUMAN (1-636): 6.24e-78: 262: 100.00
+	Hs
		148438 CPSM_HUMAN (2-1448): 0: 1504: 50.61		CTRO_HUMAN (51-557): 1.5e-16: 86.2: 14.12
+	Hs
		513578 PYC_HUMAN (367-846): 4.8e-108: 377: 18.84		TNIP1_HUMAN (1-636): 6.24e-78: 262: 100.00
+	Mm
		139162 DPYL2_MOUSE (1397-1915): 5.31e-160: 508: 17.95		FTM_MOUSE (17-526): 3.12e-25: 113: 15.30