HitPredict

Interactor 1: OBSCN (A8DYP0)
Obscurin (Inactive serine/threonine-protein kinase obscurin) (Muscle M-line assembly protein Unc-89)
Gene: Unc-89

Interactor 2: FAS2 (P34082)
Fasciclin-2 (Fasciclin II) (FAS II)
Gene: FAS2

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.80	0.658

Property	Details
Experiments	21447707, 25294943
Identification Methods	interactome parallel affinity capture, anti tag coimmunoprecipitation, pull down
Interaction Type	association

Property	Details
Interacting Pfam domains	fn3~fn3, I-set~fn3, Ig_3~fn3, I-set~I-set, Ig_3~I-set, Ig_3~Ig_3, Pkinase~fn3, I-set~Pkinase, RhoGEF~fn3
Common GO terms	-
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 4218 Dm			1 873
+	Mm
		1149039 CNTN4_MOUSE (3578-3914): 3.13e-22: 108: 11.62		CNTN4_MOUSE (228-873): 2.71e-52: 200: 13.66
+	Hs
		1336275 ROBO1_HUMAN (3605-3754): 6.41e-15: 84.4: 21.08		ROBO2_HUMAN (223-873): 1.28e-59: 223: 13.38
+	Hs
		1336269 ROBO2_HUMAN (3638-3747): 3.74e-13: 78.7: 21.19		ROBO2_HUMAN (223-873): 1.28e-59: 223: 13.38
+	Hs
		131998 CNTN6_HUMAN (3538-3877): 4.87e-14: 81.4: 14.97		NCHL1_HUMAN (1-727): 3.78e-57: 215: 14.36
+	Hs
		685309 L1CAM_HUMAN (3439-3925): 4.33e-18: 95: 8.24		CNTN2_HUMAN (218-873): 2.44e-42: 169: 11.23
+	Mm
		1167062 SDK2_MOUSE (3568-3874): 2.89e-11: 72.7: 14.15		DSCAM_MOUSE (1-867): 2.93e-48: 188: 11.37
+	Hs
		224694 KALRN_HUMAN (86-329): 8.23e-25: 117: 30.92		DSCAM_HUMAN (250-869): 1.47e-30: 132: 12.14
+	Dm
		333112 SDK_DROME (3599-3942): 9.8e-14: 80.7: 11.88		FAS2_DROME (1-518): 2.34e-42: 168: 13.25
+	Hs
		685304 L1CAM_HUMAN (3439-3925): 4.33e-18: 95: 8.24		L1CAM_HUMAN (223-873): 3.07e-37: 153: 12.65
+	Hs
		1378225 ROBO1_HUMAN (3605-3754): 6.41e-15: 84.4: 21.08		ROBO1_HUMAN (1-537): 6.68e-39: 159: 11.96
+	Dm
		1001237 DSCA1_DROME (3527-3937): 6.84e-12: 74.6: 11.40		DSCA1_DROME (1-760): 7.73e-40: 162: 12.67
+	Dm
		1000577 Q0E8G9_DROME (3476-3927): 8.97e-14: 80.7: 11.54		Q0E8G9_DROME (1-830): 1.99e-35: 148: 12.24
+	Hs
		234601 ROBO1_HUMAN (3605-3754): 6.41e-15: 84.4: 21.08		DSCAM_HUMAN (250-869): 1.47e-30: 132: 12.14
+	Rn
		222935 ROBO1_RAT (3624-3780): 3.11e-14: 82.1: 20.97		DCC_RAT (8-741): 1.1e-27: 123: 15.68
+	Mm
		93891 SDK2_MOUSE (3568-3874): 2.89e-11: 72.7: 14.15		E9QPR7_MOUSE (1-774): 6.44e-30: 130: 12.98
+	Dm
		116147 M9PHS6_DROME (3506-3927): 9.46e-14: 80.7: 12.33		M9PHS6_DROME (167-640): 1.01e-19: 97.5: 12.37
+	Dm
		1181831 Q7KSE9_DROME (3565-3919): 6.73e-19: 97.7: 9.41		Q7KSE9_DROME (152-545): 8.41e-14: 78.2: 22.46
+	Dm
		1364717 Q9VEJ5_DROME (3565-3919): 6.83e-19: 97.7: 9.41		Q9VEJ5_DROME (152-545): 1.02e-13: 77.8: 22.46
+	Mm
		1167061 SDK2_MOUSE (3568-3874): 2.89e-11: 72.7: 14.15		SDK2_MOUSE (102-519): 1.12e-14: 80.9: 24.49