Interactor 1: LEF1 (P27782)
Lymphoid enhancer-binding factor 1 (LEF-1)
Gene: LEF1

Interactor 2: HMGB2 (P30681)
High mobility group protein B2 (High mobility group protein 2) (HMG-2)
Gene: HMGB2

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 1.00 0.647

The method score is based on:

Property Details
Experiments 19805379
Identification Methods pull down
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains HMG_box~HMG_box, HMG_box~HMG_box_2
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000987 - cis-regulatory region sequence-specific DNA binding
GO:0003677 - DNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
and 7 others

more...

Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 397
Mm

1 210
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024