Interactor 1: CALR (P27797)
Calreticulin (CRP55) (Calregulin) (Endoplasmic reticulum resident protein 60) (ERp60) (HACBP) (grp60)
Gene: CALR

Interactor 2: CALX (P27824)
Calnexin (IP90) (Major histocompatibility complex class I antigen-binding protein p88) (p90)
Gene: CANX

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.62 1.00 0.789

The method score is based on:

Property Details
Experiments 10436013, 35271311
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Calreticulin~Calreticulin
Common GO terms GO:0003723 - RNA binding
GO:0005509 - calcium ion binding
GO:0005783 - endoplasmic reticulum
GO:0005788 - endoplasmic reticulum lumen
GO:0005789 - endoplasmic reticulum membrane
and 9 others

more...

Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 417
Hs

1 592
+ Hs
+ Hs
+ Mm
+ Hs
+ Oc
+ Hs
+ Hs

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Last updated: 15 Jul 2024