HitPredict

Interactor 1: PEP3 (P27801)
Vacuolar membrane protein PEP3 (Carboxypeptidase Y-deficient protein 3) (Vacuolar morphogenesis protein 8) (Vacuolar protein sorting-associated protein 18) (Vacuolar protein-targeting protein 18)
Gene: PEP3

Interactor 2: PEP3 (P27801)
Vacuolar membrane protein PEP3 (Carboxypeptidase Y-deficient protein 3) (Vacuolar morphogenesis protein 8) (Vacuolar protein sorting-associated protein 18) (Vacuolar protein-targeting protein 18)
Gene: PEP3

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.58 1.00 0.767

The method score is based on:

Property Details
Experiments 10978279, 25324549
Identification Methods two hybrid, x-ray crystallography
Interaction Type direct interaction, association, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Pep3_Vps18~Pep3_Vps18
Common GO terms GO:0000329 - fungal-type vacuole membrane
GO:0005768 - endosome
GO:0005829 - cytosol
GO:0006886 - intracellular protein transport
GO:0006895 - Golgi to endosome transport
and 16 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 918
Sc

1 918
+ Sc
+ Sc
+ Sc
+ Sc
+ Hs
+ Rn
+ Mm
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Rn
+ Dm
+ Zm
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024