Interactor 1: PEP3 (P27801)
Vacuolar membrane protein PEP3 (Carboxypeptidase Y-deficient protein 3) (Vacuolar morphogenesis protein 8) (Vacuolar protein sorting-associated protein 18) (Vacuolar protein-targeting protein 18)
Gene: PEP3

Interactor 2: VAM6 (Q07468)
Vacuolar morphogenesis protein 6 (Vacuolar protein sorting-associated protein 39)
Gene: VAM6

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 0.60 0.756

The method score is based on:

Property Details
Experiments 10944212, 25324549, 20604902, 25026036, 15889152, 29870720, 37574178, 37968396, 21325627, 22940862
Identification Methods affinity chromatography technology, biochemical, two hybrid, pull down, anti bait coimmunoprecipitation
Interaction Type physical association, association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000329 - fungal-type vacuole membrane
GO:0006886 - intracellular protein transport
GO:0007033 - vacuole organization
GO:0030897 - HOPS complex
GO:0035542 - regulation of SNARE complex assembly
and 2 others

more...

Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 918
Sc

1 1049
+ Sc
+ Sc
+ Sc
+ Sc
+ Rn
+ Mm
+ Mm
+ Hs
+ Hs
+ Hs
+ Dm
+ Hs
+ Rn
+ Hs
+ Hs
+ Hs
+ Zm
+ Hs
+ Hs

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Last updated: 15 Jul 2024