HitPredict

Interactor 1: MAP4 (P27816)
Microtubule-associated protein 4 (MAP-4)
Gene: MAP4

Interactor 2: CDC42 (P60953)
Cell division control protein 42 homolog (EC 3.6.5.2) (G25K GTP-binding protein)
Gene: CDC42

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	30217970
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0043005 - neuron projection GO:0072686 - mitotic spindle
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1152 Hs			1 191
+	Hs
		496789 TAU_HUMAN (367-1125): 2.98e-44: 174: 21.01		RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31
+	Hs
		496691 TAU_HUMAN (367-1125): 2.98e-44: 174: 21.01		CDC42_HUMAN (1-191): 4.96e-82: 243: 100.00
+	Hs
		496717 TAU_HUMAN (367-1125): 2.98e-44: 174: 21.01		RHOA_HUMAN (5-191): 3.88e-81: 240: 53.48
+	Hs
		436133 TAU_HUMAN (367-1125): 2.98e-44: 174: 21.01		RHOC_HUMAN (5-191): 3.64e-79: 235: 52.41
+	Hs
		496684 TAU_HUMAN (367-1125): 2.98e-44: 174: 21.01		RAC3_HUMAN (1-177): 2.36e-78: 233: 72.32
+	Hs
		894572 MUC12_HUMAN (5-1138): 1.61e-37: 156: 10.03		CDC42_HUMAN (1-191): 4.96e-82: 243: 100.00
+	Ce
		136793 UNC89_CAEEL (18-582): 4.82e-22: 106: 15.21		RAC1_CAEEL (1-191): 5.53e-85: 250: 65.97
+	Ce
		104464 UNC89_CAEEL (18-582): 4.82e-22: 106: 15.21		G5EBV3_CAEEL (2-191): 1e-81: 242: 58.95
+	Ce
		136794 UNC89_CAEEL (18-582): 4.82e-22: 106: 15.21		CDC42_CAEEL (1-191): 1.83e-79: 236: 86.39
+	Hs
		297840 K0754_HUMAN (721-1149): 3.99e-17: 89.8: 14.39		RHOJ_HUMAN (2-188): 2.67e-85: 252: 64.17
+	Hs
		297823 K0754_HUMAN (721-1149): 3.99e-17: 89.8: 14.39		RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31
+	Mm
		498009 TAU_MOUSE (481-1091): 8.58e-19: 94.4: 18.82		RHOG_MOUSE (1-191): 7.59e-82: 242: 60.73
+	Mm
		498148 TAU_MOUSE (481-1091): 8.58e-19: 94.4: 18.82		RHOA_MOUSE (5-191): 9.99e-82: 242: 53.48
+	Hs
		297827 K0754_HUMAN (721-1149): 3.99e-17: 89.8: 14.39		RHOG_HUMAN (1-191): 7.59e-82: 242: 60.73
+	Hs
		297820 K0754_HUMAN (721-1149): 3.99e-17: 89.8: 14.39		RHOA_HUMAN (5-191): 3.88e-81: 240: 53.48
+	Hs
		297812 K0754_HUMAN (721-1149): 3.99e-17: 89.8: 14.39		RAC2_HUMAN (1-191): 1.49e-80: 239: 68.75
+	Hs
		297809 K0754_HUMAN (721-1149): 3.99e-17: 89.8: 14.39		RHOC_HUMAN (5-191): 3.64e-79: 235: 52.41
+	Hs
		297819 K0754_HUMAN (721-1149): 3.99e-17: 89.8: 14.39		RAC3_HUMAN (1-177): 2.36e-78: 233: 72.32
+	Hs
		297834 K0754_HUMAN (721-1149): 3.99e-17: 89.8: 14.39		RHOU_HUMAN (4-186): 1.03e-72: 221: 58.82
+	Hs
		545493 MINK1_HUMAN (638-935): 1.29e-09: 65: 15.48		RAC2_HUMAN (1-191): 1.49e-80: 239: 68.75