Interactor 1: XPA (P23025)
DNA repair protein complementing XP-A cells (Xeroderma pigmentosum group A-complementing protein)
Gene: XPA

Interactor 2: XPF (Q92889)
DNA repair endonuclease XPF (EC 3.1.-.-) (DNA excision repair protein ERCC-4) (DNA repair protein complementing XP-F cells) (Xeroderma pigmentosum group F-complementing protein)
Gene: ERCC4

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.84 0.60 0.714

The method score is based on:

Property Details
Experiments 26186194, 28514442, 9013642, 33961781, unassigned3799
Identification Methods affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000110 - nucleotide-excision repair factor 1 complex
GO:0003684 - damaged DNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006281 - DNA repair
and 4 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 273
Hs

1 916
+ Ce
+ Sc

Service provided by Combinatics, Japan

Last updated: 11Aug2025