HitPredict

Interactor 1: CALX (P27824)
Calnexin (IP90) (Major histocompatibility complex class I antigen-binding protein p88) (p90)
Gene: CANX

Interactor 2: KSYK (P43405)
Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase) (p72-Syk)
Gene: SYK

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.50	0.470

Property	Details
Experiments	32814053
Identification Methods	two hybrid array, two hybrid pooling approach, validated two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 592 Hs			1 635
+	Hs
		507869 CALX_HUMAN (1-592): 0: 786: 100.00		FGFR1_HUMAN (179-635): 7.43e-116: 366: 26.24
+	Hs
		654090 CALX_HUMAN (1-592): 0: 786: 100.00		EPHA3_HUMAN (174-632): 2.58e-114: 366: 24.89
+	Hs
		161008 CLGN_HUMAN (11-546): 0: 652: 59.85		FGFR1_HUMAN (179-635): 7.43e-116: 366: 26.24
+	Hs
		337977 CALX_HUMAN (1-592): 0: 786: 100.00		EGFR_HUMAN (375-619): 8.73e-57: 209: 43.15
+	Hs
		383628 CALX_HUMAN (1-592): 0: 786: 100.00		ERBB2_HUMAN (375-619): 1.47e-52: 197: 42.34
+	Hs
		160994 CLGN_HUMAN (11-546): 0: 652: 59.85		ERBB2_HUMAN (375-619): 1.47e-52: 197: 42.34
+	Hs
		337975 CALR_HUMAN (67-470): 1.19e-141: 418: 38.33		EGFR_HUMAN (375-619): 8.73e-57: 209: 43.15