HitPredict

Interactor 1: CALX (P27824)
Calnexin (IP90) (Major histocompatibility complex class I antigen-binding protein p88) (p90)
Gene: CANX

Interactor 2: EMC2 (Q15006)
ER membrane protein complex subunit 2 (Tetratricopeptide repeat protein 35) (TPR repeat protein 35)
Gene: EMC2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.60	0.633

Property	Details
Experiments	29568061, 27342126, 35271311
Identification Methods	proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005783 - endoplasmic reticulum GO:0005789 - endoplasmic reticulum membrane GO:0034975 - protein folding in endoplasmic reticulum
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 592 Hs			1 297
+	Hs
		654463 CALX_HUMAN (1-592): 0: 786: 100.00		TMTC3_HUMAN (102-296): 1.43e-23: 102: 11.96
+	Hs
		654554 CALX_HUMAN (1-592): 0: 786: 100.00		TTC13_HUMAN (6-152): 1.29e-16: 82.1: 16.33
+	Hs
		654417 CALX_HUMAN (1-592): 0: 786: 100.00		TMTC4_HUMAN (163-293): 7.92e-11: 64.4: 12.21
+	Hs
		161083 CLGN_HUMAN (11-546): 0: 652: 59.85		TMTC4_HUMAN (163-293): 7.92e-11: 64.4: 12.21
+	Hs
		653591 CALR_HUMAN (67-470): 1.19e-141: 418: 38.33		EMC2_HUMAN (1-297): 1.09e-73: 229: 100.00
+	Hs
		174641 CALR_HUMAN (67-470): 1.19e-141: 418: 38.33		OGT1_HUMAN (21-213): 4.65e-40: 150: 11.40
+	Hs
		1173504 CALR3_HUMAN (64-470): 4.22e-135: 400: 26.59		TMTC3_HUMAN (102-296): 1.43e-23: 102: 11.96
+	Hs
		1240164 CALR3_HUMAN (64-470): 4.22e-135: 400: 26.59		TTC13_HUMAN (6-152): 1.29e-16: 82.1: 16.33