HitPredict

Interactor 1: CALX (P27824)
Calnexin (IP90) (Major histocompatibility complex class I antigen-binding protein p88) (p90)
Gene: CANX

Interactor 2: NTRK3 (Q16288)
NT-3 growth factor receptor (EC 2.7.10.1) (GP145-TrkC) (Trk-C) (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase)
Gene: NTRK3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.63	0.50	0.565

Property	Details
Experiments	32707033, 35384245
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 592 Hs			1 839
+	Hs
		161071 CLGN_HUMAN (11-546): 0: 652: 59.85		NTRK3_HUMAN (1-839): 0: 671: 100.00
+	Hs
		384315 CALX_HUMAN (1-592): 0: 786: 100.00		NTRK1_HUMAN (16-839): 8.14e-173: 520: 46.75
+	Hs
		601462 CALX_HUMAN (1-592): 0: 786: 100.00		FGFR2_HUMAN (203-838): 1.97e-168: 510: 24.89
+	Hs
		507869 CALX_HUMAN (1-592): 0: 786: 100.00		FGFR1_HUMAN (162-838): 5.94e-163: 496: 23.43
+	Hs
		607885 CALX_HUMAN (1-592): 0: 786: 100.00		FGFR4_HUMAN (166-837): 6.43e-152: 466: 24.57
+	Hs
		160995 CLGN_HUMAN (11-546): 0: 652: 59.85		NTRK1_HUMAN (16-839): 8.14e-173: 520: 46.75
+	Hs
		161008 CLGN_HUMAN (11-546): 0: 652: 59.85		FGFR1_HUMAN (162-838): 5.94e-163: 496: 23.43
+	Hs
		434139 CALX_HUMAN (1-592): 0: 786: 100.00		RET_HUMAN (282-837): 1.5e-108: 360: 25.76
+	Hs
		654272 CALX_HUMAN (1-592): 0: 786: 100.00		ROR2_HUMAN (522-828): 2.97e-67: 243: 41.56
+	Hs
		411305 CALX_HUMAN (1-592): 0: 786: 100.00		INSR_HUMAN (513-824): 1.34e-64: 238: 39.43
+	Hs
		435545 CALX_HUMAN (1-592): 0: 786: 100.00		IGF1R_HUMAN (513-820): 3.56e-64: 236: 39.16
+	Hs
		161002 CLGN_HUMAN (11-546): 0: 652: 59.85		RET_HUMAN (282-837): 1.5e-108: 360: 25.76
+	Hs
		654899 CALX_HUMAN (1-592): 0: 786: 100.00		ALK_HUMAN (513-816): 2.78e-59: 222: 39.03
+	Hs
		161053 CLGN_HUMAN (11-546): 0: 652: 59.85		ROR1_HUMAN (509-821): 2.63e-67: 243: 40.50
+	Hs
		161054 CLGN_HUMAN (11-546): 0: 652: 59.85		ROR2_HUMAN (522-828): 2.97e-67: 243: 41.56
+	Hs
		160999 CLGN_HUMAN (11-546): 0: 652: 59.85		INSR_HUMAN (513-824): 1.34e-64: 238: 39.43
+	Hs
		161003 CLGN_HUMAN (11-546): 0: 652: 59.85		IGF1R_HUMAN (513-820): 3.56e-64: 236: 39.16
+	Hs
		654302 CALX_HUMAN (1-592): 0: 786: 100.00		PTK7_HUMAN (215-380): 9.02e-12: 71.3: 17.34
+	Rn
		544766 CALR_RAT (67-470): 7.8e-147: 431: 37.35		INSR_RAT (513-824): 3.31e-62: 230: 38.80
+	At
		137905 CALR3_ARATH (62-480): 1.73e-150: 441: 32.14		BRI1_ARATH (22-426): 3.77e-18: 92.1: 12.68