HitPredict

Interactor 1: CALX (P27824)
Calnexin (IP90) (Major histocompatibility complex class I antigen-binding protein p88) (p90)
Gene: CANX

Interactor 2: VRK2 (Q86Y07)
Serine/threonine-protein kinase VRK2 (EC 2.7.11.1) (Vaccinia-related kinase 2)
Gene: VRK2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	29568061, 35271311
Identification Methods	proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005783 - endoplasmic reticulum GO:0005789 - endoplasmic reticulum membrane GO:0031966 - mitochondrial membrane
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 592 Hs			1 508
+	Hs
		654158 CALX_HUMAN (1-592): 0: 786: 100.00		KC1A_HUMAN (17-366): 5.32e-106: 321: 24.72
+	Hs
		654159 CALX_HUMAN (1-592): 0: 786: 100.00		KC1D_HUMAN (21-465): 9.4e-99: 305: 22.37
+	Hs
		654255 CALX_HUMAN (1-592): 0: 786: 100.00		KC1G2_HUMAN (24-392): 2.53e-96: 299: 22.25
+	Hs
		653515 CALR_HUMAN (67-470): 1.19e-141: 418: 38.33		KC1A_HUMAN (17-366): 5.32e-106: 321: 24.72