Interactor 1: CALX (P27824)
Calnexin (IP90) (Major histocompatibility complex class I antigen-binding protein p88) (p90)
Gene: CANX

Interactor 2: EDEM1 (Q92611)
ER degradation-enhancing alpha-mannosidase-like protein 1
Gene: EDEM1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.83 0.60 0.709

The method score is based on:

Property Details
Experiments 12610305, 22119785, 24910992, 32423001, 21632540
Identification Methods affinity chromatography technology, pull down
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005509 - calcium ion binding
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0036503 - ERAD pathway
GO:0044322 - endoplasmic reticulum quality control compartment
Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 592
Hs

1 657
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024