HitPredict

Interactor 1: CALX (P27824)
Calnexin (IP90) (Major histocompatibility complex class I antigen-binding protein p88) (p90)
Gene: CANX

Interactor 2: SEC12 (Q9HCU5)
Guanine nucleotide-exchange factor SEC12 (Prolactin regulatory element-binding protein)
Gene: PREB

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	29568061, 35271311
Identification Methods	proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005789 - endoplasmic reticulum membrane GO:0009306 - protein secretion GO:0016020 - membrane
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 592 Hs			1 417
+	Hs
		654194 CALX_HUMAN (1-592): 0: 786: 100.00		COPA_HUMAN (11-310): 2.64e-37: 146: 12.35
+	Hs
		654233 CALX_HUMAN (1-592): 0: 786: 100.00		WDR5_HUMAN (29-269): 4.37e-37: 139: 9.27
+	Hs
		653662 CALR_HUMAN (67-470): 1.19e-141: 418: 38.33		POC1A_HUMAN (142-407): 3.87e-60: 202: 15.64
+	Hs
		653530 CALR_HUMAN (67-470): 1.19e-141: 418: 38.33		COPA_HUMAN (11-310): 2.64e-37: 146: 12.35