HitPredict

Interactor 1: CALX (P27824)
Calnexin (IP90) (Major histocompatibility complex class I antigen-binding protein p88) (p90)
Gene: CANX

Interactor 2: DJB12 (Q9NXW2)
DnaJ homolog subfamily B member 12
Gene: DNAJB12

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	33957083, 35271311
Identification Methods	proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005783 - endoplasmic reticulum GO:0005789 - endoplasmic reticulum membrane GO:0016020 - membrane GO:0031965 - nuclear membrane GO:0036503 - ERAD pathway
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 592 Hs			1 375
+	Hs
		654876 CALX_HUMAN (1-592): 0: 786: 100.00		SEC63_HUMAN (87-373): 4.84e-51: 183: 19.27
+	Hs
		654869 CALX_HUMAN (1-592): 0: 786: 100.00		DNJB9_HUMAN (85-247): 2.18e-42: 149: 31.29
+	Rn
		724501 CALX_RAT (1-592): 0: 740: 91.06		DNJB9_RAT (102-239): 6.88e-46: 158: 33.81
+	Hs
		654870 CALX_HUMAN (1-592): 0: 786: 100.00		DJB11_HUMAN (109-189): 1.2e-18: 88.2: 53.66
+	Hs
		653750 CALR_HUMAN (67-470): 1.19e-141: 418: 38.33		DJB12_HUMAN (1-375): 1.18e-140: 406: 100.00
+	Hs
		1296656 CALR3_HUMAN (64-470): 4.22e-135: 400: 26.59		DJB12_HUMAN (1-375): 1.18e-140: 406: 100.00
+	Dm
		1361285 Q9VAL7_DROME (33-592): 0: 633: 49.74		Q9VS57_DROME (51-373): 7.6e-45: 166: 15.90
+	Hs
		1296662 CALR3_HUMAN (64-470): 4.22e-135: 400: 26.59		SEC63_HUMAN (87-373): 4.84e-51: 183: 19.27
+	Hs
		653760 CALR_HUMAN (67-470): 1.19e-141: 418: 38.33		DNJB9_HUMAN (85-247): 2.18e-42: 149: 31.29
+	Hs
		653761 CALR_HUMAN (67-470): 1.19e-141: 418: 38.33		DJB11_HUMAN (109-189): 1.2e-18: 88.2: 53.66
+	Hs
		1296660 CALR3_HUMAN (64-470): 4.22e-135: 400: 26.59		DJB11_HUMAN (109-189): 1.2e-18: 88.2: 53.66