HitPredict

Interactor 1: P85A (P27986)
Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase regulatory subunit alpha) (PI3K regulatory subunit alpha) (PtdIns-3-kinase regulatory subunit alpha) (Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha) (PI3-kinase subunit p85-alpha) (PtdIns-3-kinase regulatory subunit p85-alpha)
Gene: PIK3R1

Interactor 2: PTN4 (P29074)
Tyrosine-protein phosphatase non-receptor type 4 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG1) (MEG) (PTPase-MEG1)
Gene: PTPN4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	17474147
Identification Methods	peptide array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	SH2~Y_phosphatase
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 724 Hs			1 926
+	Hs
		655223 P85A_HUMAN (1-724): 0: 596: 100.00		PTN6_HUMAN (546-913): 1.07e-134: 417: 32.46
+	Hs
		576988 P85A_HUMAN (1-724): 0: 596: 100.00		PTPRA_HUMAN (639-912): 7.66e-96: 321: 33.45
+	Hs
		655375 P85A_HUMAN (1-724): 0: 596: 100.00		PTPRK_HUMAN (643-914): 1.01e-55: 212: 27.72
+	Hs
		253346 SRGP2_HUMAN (118-668): 3.41e-54: 203: 13.78		PTN13_HUMAN (618-912): 9.57e-104: 357: 35.02
+	Hs
		299236 CHIN_HUMAN (588-696): 4.99e-12: 70.8: 18.18		FARP2_HUMAN (8-507): 5.08e-133: 427: 34.40
+	Mm
		574000 FYN_MOUSE (573-724): 9.83e-33: 135: 22.50		PTPRA_MOUSE (639-912): 1.11e-95: 321: 33.45
+	Hs
		64707 RHG32_HUMAN (14-613): 1.13e-61: 227: 13.99		PTPRK_HUMAN (643-914): 1.01e-55: 212: 27.72
+	Hs
		253356 SRGP2_HUMAN (118-668): 3.41e-54: 203: 13.78		PTN14_HUMAN (30-319): 6.01e-30: 130: 31.00