HitPredict

Interactor 1: P85A (P27986)
Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase regulatory subunit alpha) (PI3K regulatory subunit alpha) (PtdIns-3-kinase regulatory subunit alpha) (Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha) (PI3-kinase subunit p85-alpha) (PtdIns-3-kinase regulatory subunit p85-alpha)
Gene: PIK3R1

Interactor 2: AKAP6 (Q13023)
A-kinase anchor protein 6 (AKAP-6) (A-kinase anchor protein 100 kDa) (AKAP 100) (Protein kinase A-anchoring protein 6) (PRKA6) (mAKAP)
Gene: AKAP6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	17474147
Identification Methods	peptide array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0048471 - perinuclear region of cytoplasm
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 724 Hs			1 2319
+	Hs
		129277 P85B_HUMAN (4-719): 6.38e-162: 486: 57.24		SPTB2_HUMAN (620-1335): 3.36e-22: 107: 8.79
+	Hs
		129220 P85B_HUMAN (4-719): 6.38e-162: 486: 57.24		MYH9_HUMAN (877-1373): 1.07e-19: 99.3: 10.37
+	Hs
		724864 RHG21_HUMAN (78-531): 1.19e-59: 221: 13.46		MYH9_HUMAN (877-1373): 1.07e-19: 99.3: 10.37
+	Hs
		724914 RHG24_HUMAN (94-443): 7.45e-57: 208: 16.76		MYH9_HUMAN (877-1373): 1.07e-19: 99.3: 10.37
+	Hs
		111443 J3QRU1_HUMAN (568-724): 2.26e-31: 131: 20.61		MYH9_HUMAN (877-1373): 1.07e-19: 99.3: 10.37
+	Hs
		433272 YES_HUMAN (568-724): 2.15e-31: 131: 20.61		MYH9_HUMAN (877-1373): 1.07e-19: 99.3: 10.37