HitPredict

Interactor 1: P85A (P27986)
Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase regulatory subunit alpha) (PI3K regulatory subunit alpha) (PtdIns-3-kinase regulatory subunit alpha) (Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha) (PI3-kinase subunit p85-alpha) (PtdIns-3-kinase regulatory subunit p85-alpha)
Gene: PIK3R1

Interactor 2: STF1 (Q13285)
Steroidogenic factor 1 (SF-1) (STF-1) (hSF-1) (Adrenal 4-binding protein) (Fushi tarazu factor homolog 1) (Nuclear receptor subfamily 5 group A member 1) (Steroid hormone receptor Ad4BP)
Gene: NR5A1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	17474147
Identification Methods	peptide array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 724 Hs			1 461
+	Hs
		587120 P85A_HUMAN (1-724): 0: 596: 100.00		RXRA_HUMAN (12-143): 5.48e-47: 170: 38.41
+	Hs
		369031 P85A_HUMAN (1-724): 0: 596: 100.00		ESR1_HUMAN (13-154): 2.14e-39: 151: 34.90
+	Hs
		129156 P85B_HUMAN (4-719): 6.38e-162: 486: 57.24		ESR1_HUMAN (13-154): 2.14e-39: 151: 34.90
+	Hs
		253301 SRGP2_HUMAN (118-668): 3.41e-54: 203: 13.78		ESR1_HUMAN (13-154): 2.14e-39: 151: 34.90
+	Hs
		368834 YES_HUMAN (568-724): 2.15e-31: 131: 20.61		ESR1_HUMAN (13-154): 2.14e-39: 151: 34.90