HitPredict

Interactor 1: P85A (P27986)
Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase regulatory subunit alpha) (PI3K regulatory subunit alpha) (PtdIns-3-kinase regulatory subunit alpha) (Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha) (PI3-kinase subunit p85-alpha) (PtdIns-3-kinase regulatory subunit p85-alpha)
Gene: PIK3R1

Interactor 2: TNIP1 (Q15025)
TNFAIP3-interacting protein 1 (A20-binding inhibitor of NF-kappa-B activation 1) (ABIN-1) (HIV-1 Nef-interacting protein) (Nef-associated factor 1) (Naf1) (Nip40-1) (Virion-associated nuclear shuttling protein) (VAN) (hVAN)
Gene: TNIP1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	17632516
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 724 Hs			1 636
+	Hs
		655386 P85A_HUMAN (1-724): 0: 596: 100.00		ITSN1_HUMAN (92-469): 5.76e-14: 77.7: 11.00
+	Hs
		129221 P85B_HUMAN (4-719): 6.38e-162: 486: 57.24		MYH10_HUMAN (210-571): 5.78e-13: 74.6: 10.48
+	Hs
		129220 P85B_HUMAN (4-719): 6.38e-162: 486: 57.24		MYH9_HUMAN (267-566): 1.17e-09: 63.8: 13.33
+	Hs
		1022676 RHG05_HUMAN (104-319): 2.41e-53: 201: 23.56		TNIP1_HUMAN (1-636): 6.24e-78: 262: 100.00
+	Hs
		1064130 RGAP1_HUMAN (14-393): 1.43e-54: 200: 15.46		TNIP1_HUMAN (1-636): 6.24e-78: 262: 100.00
+	Hs
		64621 RHG32_HUMAN (14-613): 1.13e-61: 227: 13.99		CTRO_HUMAN (51-557): 1.5e-16: 86.2: 14.12
+	Hs
		149272 RGAP1_HUMAN (14-393): 1.43e-54: 200: 15.46		CTRO_HUMAN (51-557): 1.5e-16: 86.2: 14.12
+	Hs
		724864 RHG21_HUMAN (78-531): 1.19e-59: 221: 13.46		MYH9_HUMAN (267-566): 1.17e-09: 63.8: 13.33
+	Hs
		725200 RHG24_HUMAN (94-443): 7.45e-57: 208: 16.76		MYH10_HUMAN (210-571): 5.78e-13: 74.6: 10.48
+	Hs
		724914 RHG24_HUMAN (94-443): 7.45e-57: 208: 16.76		MYH9_HUMAN (267-566): 1.17e-09: 63.8: 13.33
+	Hs
		148770 MYO9B_HUMAN (128-294): 1.43e-45: 178: 27.98		CTRO_HUMAN (51-557): 1.5e-16: 86.2: 14.12
+	Hs
		1147657 RGAP1_HUMAN (14-393): 1.43e-54: 200: 15.46		FTM_HUMAN (66-531): 2.14e-09: 62.7: 12.89
+	Hs
		111443 J3QRU1_HUMAN (568-724): 2.26e-31: 131: 20.61		MYH9_HUMAN (267-566): 1.17e-09: 63.8: 13.33
+	Hs
		433272 YES_HUMAN (568-724): 2.15e-31: 131: 20.61		MYH9_HUMAN (267-566): 1.17e-09: 63.8: 13.33