HitPredict

Interactor 1: P85A (P27986)
Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase regulatory subunit alpha) (PI3K regulatory subunit alpha) (PtdIns-3-kinase regulatory subunit alpha) (Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha) (PI3-kinase subunit p85-alpha) (PtdIns-3-kinase regulatory subunit p85-alpha)
Gene: PIK3R1

Interactor 2: HAVR2 (Q8TDQ0)
Hepatitis A virus cellular receptor 2 (HAVcr-2) (T-cell immunoglobulin and mucin domain-containing protein 3) (TIMD-3) (T-cell immunoglobulin mucin receptor 3) (TIM-3) (T-cell membrane protein 3) (CD antigen CD366)
Gene: HAVCR2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	28514442, 33961781, 26492563
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0032760 - positive regulation of tumor necrosis factor production
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1 724 Hs			1 301
+	Hs
		129319 P85B_HUMAN (4-719): 6.38e-162: 486: 57.24		HAVR2_HUMAN (1-301): 0: 542: 100.00
+	Hs
		1255249 P55G_HUMAN (271-723): 1.4e-104: 329: 72.31		HAVR2_HUMAN (1-301): 0: 542: 100.00