HitPredict

Interactor 1: P85A (P27986)
Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase regulatory subunit alpha) (PI3K regulatory subunit alpha) (PtdIns-3-kinase regulatory subunit alpha) (Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha) (PI3-kinase subunit p85-alpha) (PtdIns-3-kinase regulatory subunit p85-alpha)
Gene: PIK3R1

Interactor 2: BRD7 (Q9NPI1)
Bromodomain-containing protein 7 (75 kDa bromodomain protein) (Protein CELTIX-1)
Gene: BRD7

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.60	0.624

Property	Details
Experiments	24657164, 30940648
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 724 Hs			1 651
+	Mm
		292063 P85A_MOUSE (1-724): 0: 592: 95.99		BRD7_MOUSE (1-651): 1.51e-172: 508: 88.17
+	Hs
		129340 P85B_HUMAN (4-719): 6.38e-162: 486: 57.24		BRD7_HUMAN (1-651): 1.84e-168: 498: 100.00
+	Hs
		655501 P85A_HUMAN (1-724): 0: 596: 100.00		BRPF3_HUMAN (3-537): 1.76e-54: 203: 16.33
+	Hs
		655342 P85A_HUMAN (1-724): 0: 596: 100.00		EP300_HUMAN (42-251): 3.1e-41: 164: 22.02
+	Mm
		70897 P85A_MOUSE (1-724): 0: 592: 95.99		EP300_MOUSE (42-238): 3.03e-40: 160: 22.93
+	Hs
		70710 MYO9A_HUMAN (81-613): 5.01e-57: 213: 15.70		BRD7_HUMAN (1-651): 1.84e-168: 498: 100.00
+	Hs
		1035147 MYO9B_HUMAN (128-294): 1.43e-45: 178: 27.98		BRD7_HUMAN (1-651): 1.84e-168: 498: 100.00
+	Mm
		140054 P85B_MOUSE (287-439): 8.37e-12: 70.8: 23.38		BRD7_MOUSE (1-651): 1.51e-172: 508: 88.17
+	Hs
		631614 RHG23_HUMAN (40-369): 2.83e-52: 198: 16.80		BRD2_HUMAN (115-424): 3.01e-33: 138: 15.39
+	Hs
		1327802 RGAP1_HUMAN (14-393): 1.43e-54: 200: 15.46		BAZ2A_HUMAN (70-240): 3.27e-19: 94.9: 22.65