HitPredict

Interactor 1: P85A (P27986)
Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase regulatory subunit alpha) (PI3K regulatory subunit alpha) (PtdIns-3-kinase regulatory subunit alpha) (Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha) (PI3-kinase subunit p85-alpha) (PtdIns-3-kinase regulatory subunit p85-alpha)
Gene: PIK3R1

Interactor 2: FLRT1 (Q9NZU1)
Leucine-rich repeat transmembrane protein FLRT1 (Fibronectin-like domain-containing leucine-rich transmembrane protein 1)
Gene: FLRT1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	1.00	0.811

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	LRR_8~SH2
Common GO terms	GO:0005886 - plasma membrane GO:0005911 - cell-cell junction GO:0048471 - perinuclear region of cytoplasm
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 724 Hs			1 674
+	Hs
		129344 P85B_HUMAN (4-719): 6.38e-162: 486: 57.24		FLRT1_HUMAN (1-674): 1.15e-148: 448: 100.00
+	Hs
		1267449 P55G_HUMAN (271-723): 1.4e-104: 329: 72.31		FLRT1_HUMAN (1-674): 1.15e-148: 448: 100.00
+	Hs
		433494 YES_HUMAN (568-724): 2.15e-31: 131: 20.61		FLRT1_HUMAN (1-674): 1.15e-148: 448: 100.00