HitPredict

Interactor 1: PRP45 (P28004)
Pre-mRNA-processing protein 45
Gene: PRP45

Interactor 2: SYF1 (Q04048)
Pre-mRNA-splicing factor SYF1 (PRP19-associated complex protein 90) (Synthetic lethal with CDC40 protein 1)
Gene: SYF1

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.92 0.60 0.746

The method score is based on:

Property Details
Experiments 11283351, 11805826, 16554755, 12554883, 16429126, 18719252, 37968396
Identification Methods two hybrid pooling approach, tandem affinity purification, affinity chromatography technology, two hybrid
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0071006 - U2-type catalytic step 1 spliceosome
GO:0071007 - U2-type catalytic step 2 spliceosome
GO:0071014 - post-mRNA release spliceosomal complex
Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 379
Sc

1 859
+ Hs
+ Sc
+ Hs
+ Hs
+ Hs
+ Dm
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024