HitPredict

Interactor 1: BRAF (P28028)
Serine/threonine-protein kinase B-raf (EC 2.7.11.1) (Proto-oncogene B-Raf)
Gene: BRAF

Interactor 2: GRP75 (P38647)
Stress-70 protein, mitochondrial (75 kDa glucose-regulated protein) (GRP-75) (Heat shock 70 kDa protein 9) (Mortalin) (Peptide-binding protein 74) (PBP74) (p66 MOT)
Gene: Hspa9

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	27034005
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005739 - mitochondrion
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 751 Mm			1 679
+	Mm
		655941 BRAF_MOUSE (31-751): 0: 699: 100.00		HSP7C_MOUSE (51-653): 0: 886: 50.16
+	Hs
		503368 BRAF_HUMAN (31-751): 0: 676: 90.90		HSP7C_HUMAN (51-653): 0: 886: 50.16
+	Hs
		542812 BRAF_HUMAN (31-751): 0: 676: 90.90		HSP76_HUMAN (49-673): 0: 880: 48.68
+	Hs
		542834 BRAF_HUMAN (31-751): 0: 676: 90.90		GRP75_HUMAN (1-679): 0: 880: 98.38
+	Gg
		251126 BRAF_CHICK (37-751): 0: 657: 89.99		HSP7C_CHICK (51-653): 0: 881: 50.00
+	Gg
		982839 BRAF_CHICK (37-751): 0: 657: 89.99		GRP75_CHICK (1-679): 0: 875: 90.47
+	Hs
		373593 RAF1_HUMAN (126-740): 1.21e-172: 512: 56.15		HSP7C_HUMAN (51-653): 0: 886: 50.16
+	Hs
		373642 RAF1_HUMAN (126-740): 1.21e-172: 512: 56.15		HSP76_HUMAN (49-673): 0: 880: 48.68
+	Hs
		373811 RAF1_HUMAN (126-740): 1.21e-172: 512: 56.15		GRP75_HUMAN (1-679): 0: 880: 98.38
+	Hs
		374331 RAF1_HUMAN (126-740): 1.21e-172: 512: 56.15		Q53FC7_HUMAN (49-673): 0: 876: 48.37
+	Hs
		488545 ARAF_HUMAN (124-735): 6.32e-164: 488: 56.17		HSP7C_HUMAN (51-653): 0: 886: 50.16
+	Hs
		488563 ARAF_HUMAN (124-735): 6.32e-164: 488: 56.17		HSP76_HUMAN (49-673): 0: 880: 48.68
+	Hs
		488602 ARAF_HUMAN (124-735): 6.32e-164: 488: 56.17		GRP75_HUMAN (1-679): 0: 880: 98.38
+	Hs
		384163 NTRK1_HUMAN (106-707): 2.27e-127: 400: 18.57		HSP7C_HUMAN (51-653): 0: 886: 50.16
+	Mm
		588704 BRAF_MOUSE (31-751): 0: 699: 100.00		BIP_MOUSE (53-677): 0: 562: 51.50
+	Hs
		501634 BRAF_HUMAN (31-751): 0: 676: 90.90		BIP_HUMAN (53-677): 0: 561: 50.08
+	Gg
		982845 BRAF_CHICK (37-751): 0: 657: 89.99		BIP_CHICK (53-677): 0: 565: 51.65
+	Hs
		373591 RAF1_HUMAN (126-740): 1.21e-172: 512: 56.15		BIP_HUMAN (53-677): 0: 561: 50.08
+	Hs
		488544 ARAF_HUMAN (124-735): 6.32e-164: 488: 56.17		BIP_HUMAN (53-677): 0: 561: 50.08
+	Hs
		384161 NTRK1_HUMAN (106-707): 2.27e-127: 400: 18.57		BIP_HUMAN (53-677): 0: 561: 50.08