Interactor 1: BRAF (P28028)
Serine/threonine-protein kinase B-raf (EC 2.7.11.1) (Proto-oncogene B-Raf)
Gene: BRAF

Interactor 2: RASH (Q61411)
GTPase HRas (EC 3.6.5.2) (H-Ras-1) (Transforming protein p21) (c-H-ras) (p21ras) [Cleaved into: GTPase HRas, N-terminally processed]
Gene: Hras

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.60 1.00 0.775

The method score is based on:

Property Details
Experiments 8668348, 27034005
Identification Methods two hybrid, affinity chromatography technology
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains C1_1~Ras, RBD~Ras
Common GO terms GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0007265 - Ras protein signal transduction
GO:0010628 - positive regulation of gene expression
GO:0042127 - regulation of cell population proliferation
and 4 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 751
Mm

1 189
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024